Bioengineering Lecture

We create engineered protein ligands and receptors with altered biochemical and biophysical properties with several goals in mind. For example, these engineered proteins are being used as tools for studying the relationship between properties such as binding kinetics and affinity, and biological effects like cell signaling, proliferation, and migration. We are also developing these engineered proteins as therapeutics and diagnostic agents for biomedical applications including cancer and regenerative medicine. I will highlight a few examples of engineered proteins from my lab with translational impact, as well as present high-throughput screening technology that has enabled new applications in protein engineering.