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X-WR-CALNAME:Caltech Brain Imaging Center Seminar
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SUMMARY:The Future of fMRI: Challenges\, Opportunities\, and Ultimate Util
 ity
DTSTART;TZID=America/Los_Angeles:20240531T103000
DTEND;TZID=America/Los_Angeles:20240531T113000
DTSTAMP:20241112T115603Z
UID:Caltech Brain Imaging Center Seminar@Fri May 31 10:30:00 2024@main.osc
 web.caltech.edu
CATEGORIES:
DESCRIPTION:Peter Bandettini\, NIH/NIMH\nIt's been about 32 years since th
 e first functional MRI (fMRI) signals were observed and since then\, as it
  has grown in sophistication and utility\, the number of groups using it a
 s their primary investigative tool has grown. Likewise\, the range and dep
 th of neuroscience questions addressed has also increased. Advances have o
 ccurred in acquisition approaches\, processing methods\, our insight into 
 the mechanisms behind the signal\, and applications. In this talk\, this p
 rogression will be traced\, highlighting some of the more significant adva
 nces. The bulk of this talk will be devoted to the question of where fMRI 
 is going. What are the major challenges and most promising opportunities o
 r direction in the field today? How will the method achieve more clinical 
 traction?\nSpecifically\, the future of several areas of fMRI will be high
 lighted. Among these are: the growth of large\, shared databases\, ultra-h
 igh resolution fMRI - specifically cortical depth-resolved fMRI\, the deve
 lopment of novel pulse sequences like multi-echo fMRI and simultaneous con
 trasts\, the potential of deep sampling of data to draw more subtle infere
 nces and to delineate more clearly differences and similarities between in
 dividuals\, the use of voxel-wise predictive modeling as well as intersubj
 ect correlation approaches\, real-time neurofeedback\, multi-modal integra
 tion\, novel and perhaps direct neuronal contrasts\, and the most compelli
 ng immediate clinical applications.\nAlso discussed are challenges that ha
 ve been present since the beginning such as image distortion\, physiologic
  noise and motion\, the confining space and high acoustic noise associated
  with MRI\, and the ubiquity of variable hemodynamics as we continuously m
 ove towards higher spatial and temporal resolution. Lastly\, I will conclu
 de with my own projections of where fMRI might be in the next 5\, 10\, and
  20 years in terms of dissemination\, technology\, and utility.\nThis semi
 nar is part of the "Future Advances in Multi-modal Neuroimaging Methods" s
 eries. Existing methods for measuring human brain function non-invasively 
 such as fMRI\, MEG and EEG have helped to considerably advance our underst
 anding of human brain function over the past several decades. However\, th
 ese methods suffer from substantial limitations in spatial and temporal re
 solution\, thereby imposing major constraints on the kinds of neuroscience
  research questions that can be addressed in humans. This seminar series e
 xplores cutting-edge new technologies and methodologies for multi-modal im
 aging. We will ask whether such new approaches have the potential to overc
 ome existing limitations and open up new research directions in human neur
 oscience over the coming decades.
LOCATION:Online Event
URL:https://www.caltech.edu/campus-life-events/calendar/cbic-seminar-bande
 ttini
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